Dysplastic nevus
☆ Ninu awọn abajade 2022 Stiftung Warentest lati Jẹmánì, itẹlọrun alabara pẹlu ModelDerm jẹ kekere diẹ ju pẹlu awọn ijumọsọrọ telemedicine isanwo.
Dysplastic nevi ― Biopsy jẹ iṣeduro fun awọn ara Iwọ-oorun.
References
Dysplastic nevus , ti a tun mọ ni atypical tabi Clarks nevus, ti fa awọn ariyanjiyan ni Ẹkọ-ara ati Ẹkọ-ara. Awọn oniṣegun nigbagbogbo biopsy awọn moles wọnyi nitori wọn le dabi ohun ajeji ati gbe awọn ifiyesi dide nipa melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , tun mọ bi atypical tabi Clark nevi, le ma ja si melanoma. Nipa 36% ti melanomas wa nitosi dysplastic nevi. Awọn ami ti nevus dysplastic le yipada si melanoma pẹlu apẹrẹ ti ko ni deede, awọn iyipada pigmenti diẹ sii, tabi awọ grẹyish kan. Awọn aarun wọnyi maa n ṣẹlẹ ni ọjọ ori (ni ayika aarin-ọgbọn ọdun) , le jẹ pupọ, ati nigbagbogbo wa lori ẹhin mọto. Ni ipilẹṣẹ, dysplastic nevi wa laarin nevi ti ko dara ati melanoma. Sibẹsibẹ, ida 20% si 30% melanoma wa lati inu nevi to wa tẹlẹ.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma jẹ iru tumo ti o dagba nigbati melanocytes, awọn sẹẹli ti o ni iduro fun awọ ara, di alakan. Melanocytes wa lati inu iṣan ti iṣan. Eyi tumọ si pe melanomas le dagbasoke kii ṣe lori awọ ara nikan ṣugbọn tun ni awọn agbegbe miiran nibiti awọn sẹẹli alakan ti n lọ kiri, bii ikun ikun ati ọpọlọ. Oṣuwọn iwalaaye fun awọn alaisan ti o ni melanoma ni ibẹrẹ-ipele (ipele 0) ga ni 97%, lakoko ti o lọ silẹ ni pataki si iwọn 10% fun awọn ti o ni ayẹwo pẹlu arun ipele to ti ni ilọsiwaju (ipele IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ ewu akàn
Gẹgẹbi a ti rii ni awọn eniyan Caucasian ni Amẹrika, awọn ti o ni dysplastic nevi ni eewu igbesi aye ti idagbasoke melanoma ti o tobi ju 10%. Ni apa keji, awọn ti ko ni nevus dysplastic ni eewu ti idagbasoke melanoma ti o kere ju 1%.
○ Iṣọra fun awọn ẹni-kọọkan pẹlu dysplastic nevi
Ayẹwo ara ẹni ni a ṣe iṣeduro nigbagbogbo fun idilọwọ melanoma (nipa idanimọ nevi atypical ti o le yọ kuro) tabi fun wiwa ni kutukutu ti awọn èèmọ to wa tẹlẹ. Awọn eniyan ti o ni itan-akọọlẹ ti ara ẹni tabi ti idile ti akàn ara tabi ti nevi atypical pupọ yẹ ki o wo onimọ-ara kan o kere ju lẹẹkan lọdun lati rii daju pe wọn ko ni idagbasoke melanoma.
Awọn abbreviation [ABCDE] ti jẹ iwulo fun iranlọwọ awọn olupese ilera ati awọn eniyan lasan ranti awọn abuda pataki ti melanoma. Laanu fun eniyan apapọ, ọpọlọpọ awọn keratoses seborrheic, diẹ ninu awọn lentigo senilis, ati paapaa warts le ni awọn abuda [ABCDE], ati pe a ko le ṣe iyatọ si melanoma.
○ [ABCDE]
Asymmetrical: Asymmetrical ara egbo.
Border: Aala ti ọgbẹ jẹ alaibamu.
Color: melanomas nigbagbogbo ni ọpọ alaibamu awọn awọ.
Diameter: nevi ti o tobi ju 6 mm jẹ diẹ sii lati jẹ melanomas ju nevi kekere lọ.
Evolution: Awọn itankalẹ (ie iyipada) ti nevus tabi ọgbẹ le fihan pe ọgbẹ naa ti di alaimọ.